He's not a medic, but chakra exhaustion is when you run low on the chakra in your body, as a result of pushing it outside of yourself to perform techniques. If you were using entirely yin chakra for some reason, it'll have solely mental effects, while if you were using entirely yang chakra, solely physical - fatigue, lack of focus, confusion, disorientation, and lack of executive function are the main yin exhaustion symptoms, and yang exhaustion mimics hypothermia for the most part. Almost all techniques use both yin and yang chakra. Chakra exhaustion can take days to recover from, and severe cases can result in death or permanent disability.
He's not certain the transformations are technically an enchantment any more than calcification diseases are enchantments, but he doesn't know how 'Break Enchantment' would work. But again he's not a specialist; the Sage animals, the Hokage, or one of the friendlier Tailed Beasts - probably Matatabi - would be the ones to talk to. He doesn't expect most people would prefer being an inert tree over being a walking, talking tree, though.
(The Sage animals are particularly intelligent and powerful members of certain summons clans - summons here are animals with sapience, who can use chakra and often grow to great sizes. Sage animals, like Sage humans, have mastered the use of nature chakra. The Tailed Beasts are nine creatures, each significantly more powerful than any human. All nine of them have some territory they claim, and tend to defend it from incursion. The three weakest - Shukaku, Matatabi, and Isobu - are also the only three willing to talk to humans, and therefore the only ones they know the names of, and of those three Matatabi and Shukaku are considered the only ones to actually have a vaguely human-compatible mindset. Shukaku spends all of his time drinking or unconscious. Matatabi will sometimes entertain visitors in her mountains, and Tobirama's spoken to her a few times. She helped him with developing some techniques.)
Blindness is the main disability their current ninja have to deal with, since it afflicts one particular clan. Of course, there's other clans with other tendencies elsewhere.
He'll be cautious with storage magic experimentation, then.